SCHEMBL8088826

SCHEMBL8088826

[3H]c1cc2c(c([3H])c1[3H])C(=O)N(OC(C)=O)C2=O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
ELANE P08246 1/20 0.31
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080590 0.89 ALDH1A1 (0.36) KDRALDH1A1CYP1A2CYP2C9ELANE
SCHEMBL859822 0.78 ALDH1A1 (0.47) KDRALDH1A1CYP1A2CYP2C9ELANE
SCHEMBL29838651 0.78 ALDH1A1 (0.47) KDRALDH1A1CYP1A2CYP2C9ELANE
SCHEMBL8087952 0.75 ALDH1A1 (0.51) ALDH1A1CYP1A2
SCHEMBL8088866 0.75 ALDH1A1 (0.48) ALDH1A1CYP1A2
SCHEMBL5865397 0.74 NPC1 (0.50) KDRALDH1A1CES1
SCHEMBL13814011 0.71 CA9 (0.49) ALDH1A1
SCHEMBL8080584 0.70 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CES1
SCHEMBL8088825 0.70 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CES1
SCHEMBL8080588 0.70 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6160128-A Tritioacetylating reagents and processes for preparation thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-12-12 US claimed
US-6160128-A Tritioacetylating reagents and processes for preparation thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-12-12 US disclosed