Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.35 |
| ▸ | GRM8 | O00222 | 3/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088591 | 1.00 | GRM2 (0.42) | GRM2GRM5GRM1GRM4GRM8 | |
| SCHEMBL8088366 | 1.00 | GRM2 (0.42) | GRM2GRM5GRM1GRM4GRM8 | |
| SCHEMBL1954837 | 0.77 | — | — | |
| SCHEMBL2790345 | 0.77 | — | — | |
| SCHEMBL14647435 | 0.77 | — | — | |
| SCHEMBL3294258 | 0.77 | — | — | |
| SCHEMBL594504 | 0.77 | — | — | |
| SCHEMBL16240415 | 0.77 | — | — | |
| SCHEMBL8274144 | 0.77 | — | — | |
| SCHEMBL8245300 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009008913-A2 | P1-NONEPIMERIZABLE KETOAMIDE INHIBITORS OF HCV NS3 PROTEASE | SCHERING CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |