Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 16/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 16/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390918 | 0.86 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1HRH3 | |
| SCHEMBL6180585 | 0.80 | CYP11B1 (0.44) | CYP11B1CYP11B2HRH3LOXL2 | |
| SCHEMBL5891862 | 0.79 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL8174417 | 0.78 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8298245 | 0.78 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8387542 | 0.77 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8097809 | 0.77 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7475351 | 0.77 | CYP11B1 (0.71) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7507201 | 0.77 | CYP11B1 (0.74) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7473109 | 0.76 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |