Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.45 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.45 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.45 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.45 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.45 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.45 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791472 | 0.94 | PSMB11 (0.51) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL5791476 | 0.94 | PSMB11 (0.51) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL5794871 | 0.92 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL5794870 | 0.92 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL8089119 | 0.92 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL31306995 | 0.92 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL8089117 | 0.86 | — | — | |
| SCHEMBL30163450 | 0.84 | CNR1 (0.49) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL29498993 | 0.83 | PSMB11 (0.45) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL270119 | 0.81 | HDAC6 (0.39) | TAS1R3TAS1R1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758361-B1 | POLYMERISABLE COMPOSITION AND THE USE THEREOF | NOVARTIS AG (CH) | 2000-11-15 | — | — | EP | disclosed |
| US-5852126-A | Polymerisable composition and the use thereof | NOVARTIS AG (CH) | 1998-12-22 | — | — | US | disclosed |