SCHEMBL8089115

SCHEMBL8089115

COC(=O)c1ccccc1S(=O)(=O)N(C(N)=O)c1nc(OC(F)F)cc(OC(F)F)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.37
SLC40A1 Q9NP59 1/20 0.36
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
PTPN5 P54829 1/20 0.35
HSD17B10 Q99714 2/20 0.34
ALDH1A1 P00352 2/20 0.34
CFTR P13569 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SDHB P21912 1/20 0.34
BRD4 O60885 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8429405 0.90 CA1 (0.43) CA1CA2CA5ACA9KMT2A
SCHEMBL1535827 0.88 F2 (0.38) CA1CA2CA9KMT2AMEN1
SCHEMBL9368406 0.83 CA1 (0.44) CA1CA2CA5ACA9KMT2A
SCHEMBL6054812 0.82 CA1 (0.50) CA1CA2CA5ACA9KMT2A
SCHEMBL9743094 0.80 CA1 (0.47) CA1CA2CA5ACA9KMT2A
SCHEMBL11007188 0.79 KMT2A (0.42) CA1CA2CA5ACA9KMT2A
SCHEMBL9452140 0.79 CA1 (0.40) CA1CA2CA5ACA9KMT2A
SCHEMBL8463982 0.78 KEAP1 (0.33) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL10803109 0.78 CA1 (0.45) CA1CA2CA5ACA9KMT2A
SCHEMBL9730399 0.76 CA1 (0.45) CA1CA2CA5ACA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0768033-B1 HERBICIDAL COMPOSITION IDEMITSU KOSAN CO (JP) 1999-12-08 EP claimed
US-5759955-A SYNERGISTIC MIXTURES WITH OTHER HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-02 US claimed
EP-0768033-A1 HERBICIDAL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-04-16 EP claimed
EP-1053679-A1 Herbicidal compositions AVENTIS CROPSCIENCE S.A. (FR) 2000-11-22 EP disclosed
EP-0768033-B1 HERBICIDAL COMPOSITION IDEMITSU KOSAN CO (JP) 1999-12-08 EP disclosed
US-5773703-A Herbicide resistant rice BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 1998-06-30 US disclosed
US-5759955-A SYNERGISTIC MIXTURES WITH OTHER HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed
US-5736629-A PLANT EXPRESSES A MUTANT ACETOHYDROXYACID SYNTHASE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 1998-04-07 US disclosed
EP-0768033-A1 HERBICIDAL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-04-16 EP disclosed