Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5631916 | 0.87 | OPRK1 (0.80) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL6480763 | 0.84 | OPRK1 (0.78) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL6359695 | 0.84 | OPRK1 (0.75) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL5631993 | 0.83 | OPRK1 (1.00) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL17870633 | 0.83 | OPRK1 (1.00) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL5655311 | 0.81 | OPRK1 (0.73) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL7176760 | 0.81 | OPRK1 (0.75) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL5629650 | 0.81 | OPRK1 (0.75) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL16379856 | 0.77 | OPRK1 (0.67) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 | |
| SCHEMBL6478584 | 0.77 | OPRK1 (0.82) | OPRK1CYP2D6OPRM1OPRD1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028063-A | ADMINISTERING COMPOUND WITH OPIOID ACTIVITY | ADOLOR CORPORATION (US) | 2000-02-22 | — | — | US | claimed |