SCHEMBL8089192

SCHEMBL8089192

CC(=Cc1ccccc1)c1ccc(O)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.80
ESR2 Q92731 4/20 0.80
PTGS1 P23219 7/20 0.66
NQO2 P16083 4/20 0.66
PTGS2 P35354 4/20 0.66
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP19A1 P11511 2/20 0.47
ALDH2 P05091 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
HSPD1 P10809 1/20 0.47
F3 P13726 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
HSPE1 P61604 1/20 0.47
CYP1B1 Q16678 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089190 1.00 ESR1 (0.80) ESR1ESR2PTGS1NQO2PTGS2
Phenol SCHEMBL9037691 0.94 ESR1 (0.84) ESR1ESR2PTGS1NQO2PTGS2
Phenol SCHEMBL9037693 0.94 ESR1 (0.84) ESR1ESR2PTGS1NQO2PTGS2
SCHEMBL8712456 0.92 ESR1 (0.80) ESR1ESR2PTGS1NQO2PTGS2
SCHEMBL8712455 0.92 ESR1 (0.80) ESR1ESR2PTGS1NQO2PTGS2
SCHEMBL7803180 0.91 ESR1 (0.64) ESR1ESR2PTGS1NQO2PTGS2
SCHEMBL375018 0.89 ESR1 (1.00) ESR1ESR2PTGS1NQO2PTGS2
SCHEMBL9036145 0.89 ESR1 (1.00) ESR1ESR2PTGS1NQO2PTGS2
SCHEMBL9036138 0.89 ESR1 (1.00) ESR1ESR2PTGS1NQO2PTGS2
SCHEMBL375017 0.89 ESR1 (1.00) ESR1ESR2PTGS1NQO2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379057-B1 Mesogenic epoxy compounds DOW CHEMICAL CO (US) 2000-12-06 EP disclosed
EP-0409069-B1 Mesogenic polycyanates and polycyanamides and thermosets thereof DOW CHEMICAL CO (US) 1999-06-02 EP disclosed
EP-0409070-B1 Mesogenic cyanite functional maleimides and thermosets thereof DOW CHEMICAL CO (US) 1999-03-03 EP disclosed
US-5736620-A ENHANCED UNIDIRECTIONAL, MECHANICAL PROPERTIES AT LOWER TEMPERATURE THE DOW CHEMICAL COMPANY (US) 1998-04-07 US disclosed
US-5612479-A Polyphenols containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1997-03-18 US disclosed
US-5470946-A Products resulting from polymerizing or curing polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1995-11-28 US disclosed
US-5463091-A Liquid crystals, polyepoxides THE DOW CHEMICAL COMPANY (US) 1995-10-31 US disclosed
US-5442039-A Rod-like mesogenic structures incorporated into polytriazine products; improved tensile strength, flexural strength THE DOW CHEMICAL COMPANY (US) 1995-08-15 US disclosed
US-5428125-A Liquid crystalline THE DOW CHEMICAL COMPANY (US) 1995-06-27 US disclosed
US-5391651-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1995-02-21 US disclosed
US-5248758-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5248757-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5227452-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-07-13 US disclosed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US disclosed
US-5206321-A Polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1993-04-27 US disclosed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP disclosed
US-5077380-A Mesogenic cyanate functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-12-31 US disclosed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
EP-0409070-A2 Mesogenic cyanite functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
EP-0379057-A2 Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed