Phenol

Phenol

SCHEMBL9037693

CC(=Cc1ccc(O)cc1)c1ccc(O)cc1.Oc1ccccc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.84
ESR2 Q92731 3/20 0.84
PTGS1 P23219 8/20 0.64
PTGS2 P35354 5/20 0.64
NQO2 P16083 4/20 0.64
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL9037691 1.00 ESR1 (0.84) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8712456 0.94 ESR1 (0.80) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8089192 0.94 ESR1 (0.80) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8712455 0.94 ESR1 (0.80) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8089190 0.94 ESR1 (0.80) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL375018 0.92 ESR1 (1.00) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL9036145 0.92 ESR1 (1.00) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL375017 0.92 ESR1 (1.00) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL9036138 0.92 ESR1 (1.00) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL7759808 0.92 ESR1 (1.00) ESR1ESR2PTGS1PTGS2NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708796-A1 PROCESS FOR PREPARING COMPOSITES BASED ON ORIENTED MESOGENIC THERMOSET RESINS THE DOW CHEMICAL COMPANY (US) 1996-05-01 EP disclosed
WO-1994026690-A1 BIS(AMINOPHENOXY)-ALPHA-SUBSTITUTED STILBENES, CURABLE MIXTURES WITH EPOXY RESINS AND CURED PRODUCTS THE DOW CHEMICAL COMPANY (US) 1994-11-24 WO disclosed