Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.43 |
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089198 | 1.00 | NPC1 (0.55) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL11316388 | 0.91 | NPC1 (0.48) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL10604233 | 0.91 | EGFR (0.62) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL11316384 | 0.91 | NPC1 (0.48) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL10624387 | 0.91 | EGFR (0.62) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL11316218 | 0.91 | EGFR (0.62) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL10624379 | 0.91 | EGFR (0.62) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL11316220 | 0.91 | EGFR (0.62) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL16153082 | 0.89 | KMT2A (0.62) | NPC1RAB9AEGFRMEN1KMT2A | |
| SCHEMBL14690238 | 0.89 | EGFR (0.66) | NPC1RAB9AEGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646158-B | The preparation and use of three aldehyde of cyclodoecatriene and related compound | 陶氏环球技术有限责任公司 | 2018-07-06 | — | — | CN | disclosed |
| EP-0379057-B1 | Mesogenic epoxy compounds | DOW CHEMICAL CO (US) | 2000-12-06 | — | — | EP | disclosed |
| US-5736620-A | ENHANCED UNIDIRECTIONAL, MECHANICAL PROPERTIES AT LOWER TEMPERATURE | THE DOW CHEMICAL COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5463091-A | Liquid crystals, polyepoxides | THE DOW CHEMICAL COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| US-5292831-A | Enhanced unidirectional, mechanical properties | THE DOW CHEMICAL COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5270405-A | Mesogenic epoxy compounds | THE DOW CHEMICAL COMPANY (US) | 1993-12-14 | — | — | US | disclosed |
| US-5270404-A | Curable compositions of mesogen-containing advanced epoxy resins and curing agents therefor | THE DOW CHEMICAL COMPANY (US) | 1993-12-14 | — | — | US | disclosed |
| US-5266660-A | Curable compositions containing mesogenic epoxy compounds and cured products thereof | THE DOW CHEMICAL CO. (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0379057-A2 | Mesogenic epoxy compounds | THE DOW CHEMICAL COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |