SCHEMBL8089327

SCHEMBL8089327

C=CC(=O)OC(O)(O)CCCC

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.50
HPGD P15428 1/20 0.50
THRB P10828 4/20 0.39
ALDH1A1 P00352 4/20 0.36
CYP3A4 P08684 2/20 0.36
THRA P10827 1/20 0.36
ATM Q13315 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11032506 0.94 TSHR (0.48) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL4235846 0.88 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL28345184 0.83 TSHR (0.48) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL31609320 0.82 TSHR (0.52) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL3234096 0.81 TSHR (0.50) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL29372293 0.81 TSHR (0.50) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL28780914 0.81 TSHR (0.50) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL5873986 0.79 AKR1B1 (0.36) TSHRALDH1A1MAPK1HSD17B10
SCHEMBL996460 0.79 THRB (0.43) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL8965835 0.79 TSHR (0.59) TSHRHPGDTHRBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4379864-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1983-04-12 US claimed
US-4267295-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1981-05-12 US claimed
CN-122018054-A Antireflection film and preparation method thereof 江苏日久光电股份有限公司 2026-05-12 CN disclosed
EP-0889917-B1 NOVEL POLYMERIC SULFIDE MINERAL DEPRESSANTS CYTEC TECH CORP (US) 2000-11-02 EP disclosed
US-5959054-A TERPOLYMER CONTAINING ACRYLAMIDE, ALLYL THIOUREA AND HYDROXYETHYL ACRYLATE CYTEC TECHNOLOGY CORP. (US) 1999-09-28 US disclosed
EP-0889917-A1 NOVEL POLYMERIC SULFIDE MINERAL DEPRESSANTS Cytec Technology Corp. (US) 1999-01-13 EP disclosed
US-5756622-A TERPOLYMER OF (METH)ACRYLAMIDE, ALLYL THIOUREA AND HYDROXYALKYL (METH)ACRYLATE CYTEC TECHNOLOGY CORP. (US) 1998-05-26 US disclosed
WO-1997035897-A1 NOVEL POLYMERIC SULFIDE MINERAL DEPRESSANTS CYTEC TECHNOLOGY CORP. (US) 1997-10-02 WO disclosed
US-4543371-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1985-09-24 US disclosed
US-4379864-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1983-04-12 US disclosed
US-4267295-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1981-05-12 US disclosed