Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544214 | 0.84 | CNR2 (0.79) | CNR2LMNATHRBTP53MDM2 | |
| SCHEMBL4417012 | 0.83 | CNR2 (0.79) | CNR2THRBPOLB | |
| SCHEMBL4408549 | 0.73 | CNR2 (0.83) | CNR2ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL4409929 | 0.73 | CNR2 (1.00) | CNR2 | |
| SCHEMBL4411949 | 0.73 | CNR2 (0.82) | CNR2GRM5TP53MDM2 | |
| SCHEMBL4405983 | 0.73 | CNR2 (1.00) | CNR2 | |
| SCHEMBL8091179 | 0.72 | CNR2 (1.00) | CNR2LMNAALDH1A1GAAMAPT | |
| SCHEMBL4409562 | 0.72 | CNR2 (0.84) | CNR2LMNAALDH1A1GAAMAPT | |
| SCHEMBL4411477 | 0.71 | CNR2 (1.00) | CNR2LMNAALDH1A1POLB | |
| SCHEMBL4418089 | 0.71 | CNR2 (0.82) | CNR2ALDH1A1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |