Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078040 | 0.82 | CNR2 (0.69) | CNR2LMNAALDH1A1 | |
| SCHEMBL4405983 | 0.80 | CNR2 (1.00) | CNR2 | |
| SCHEMBL4409616 | 0.78 | CNR2 (1.00) | CNR2GAAALDH1A1MAPTHTT | |
| SCHEMBL8085081 | 0.77 | CNR2 (0.62) | CNR2GAAALDH1A1MAPTHTT | |
| SCHEMBL8085623 | 0.77 | CNR2 (0.71) | CNR2HTT | |
| SCHEMBL4368102 | 0.75 | CNR2 (0.59) | CNR2LMNAGAAALDH1A1MAPT | |
| SCHEMBL4408457 | 0.74 | CNR2 (1.00) | CNR2LMNA | |
| SCHEMBL8089408 | 0.73 | CNR2 (0.65) | CNR2 | |
| SCHEMBL4551332 | 0.73 | CNR2 (0.89) | CNR2LMNAALDH1A1 | |
| SCHEMBL4411502 | 0.72 | CNR2 (0.63) | CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |