SCHEMBL8089392

SCHEMBL8089392

Cc1c(SCCCSc2ccc3ncc([N+](=O)[O-])n3n2)ccnc1C(S)c1ncccn1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089465 0.93 ALDH1A1 (0.33) CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL8088307 0.88 CYP1A2 (0.30) CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL8088371 0.84
SCHEMBL8092765 0.82 CYP1A2 (0.35) CYP1A2CYP2C9
SCHEMBL8089394 0.81 CYP1A2 (0.32) CYP1A2CYP2C9
SCHEMBL8082681 0.81 CYP1A2 (0.34) CYP1A2CYP2C9
SCHEMBL8081086 0.81 CYP1A2 (0.36) CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL8088374 0.80
Hydrochloric Acid SCHEMBL8092771 0.80
SCHEMBL8081188 0.79 CYP1A2 (0.33) CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6043242-A TREATING A MAMMAL AFFLICTED WITH A DISEASE BASED ON HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-03-28 US disclosed
EP-0946559-A2 IMIDAZOPYRIDAZINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1999-10-06 EP disclosed
WO-1998028299-A2 IMIDAZOPYRIDAZINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1998-07-02 WO disclosed