SCHEMBL8089409

SCHEMBL8089409

O=C(OP)C1C[C@H](O)CN1P

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.36
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19178269 0.83
SCHEMBL13254475 0.82 ALDH1A1 (0.49) ATMALDH1A1
SCHEMBL8093974 0.82 ALDH1A1 (0.49) ATMALDH1A1
SCHEMBL8090066 0.82 ALDH1A1 (0.49) ATMALDH1A1
SCHEMBL13254467 0.82 PEPD (0.32)
SCHEMBL18924854 0.82 PEPD (0.32)
SCHEMBL18924899 0.77
SCHEMBL6678799 0.77 ATM (0.53) ATM
SCHEMBL8271333 0.77 ATM (0.53) ATM
SCHEMBL13614138 0.77 ATM (0.53) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2178902-B1 MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS ANGELETTI P IST RICHERCHE BIO (IT) 2012-11-28 EP disclosed
WO-2009010804-A1 MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2009-01-22 WO disclosed