Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247143 | 0.88 | MAPT (0.46) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL30860757 | 0.82 | ALDH1A1 (0.47) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL2241580 | 0.80 | MAPT (0.44) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL29739434 | 0.80 | MAPT (0.44) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| Carbamic Acid SCHEMBL26633282 | 0.79 | MAPT (0.41) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL8084394 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL12365761 | 0.76 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL14141980 | 0.72 | ALDH1A1 (0.59) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL26133140 | 0.71 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 | |
| SCHEMBL10843250 | 0.70 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1ALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147812-A2 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-12-04 | — | — | WO | disclosed |