Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 9/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30272627 | 0.92 | GPR119 (0.61) | GPR119EPHX2ALKHRH3 | |
| SCHEMBL22462765 | 0.92 | GPR119 (0.61) | GPR119EPHX2ALKHRH3 | |
| SCHEMBL14087517 | 0.88 | GPR119 (0.67) | GPR119ALKHRH3 | |
| SCHEMBL951252 | 0.86 | GPR119 (0.65) | GPR119ALKARHRH3 | |
| SCHEMBL25930392 | 0.86 | GPR119 (0.53) | GPR119ALKAR | |
| SCHEMBL3283465 | 0.85 | GPR119 (0.64) | GPR119ALKARHRH3 | |
| SCHEMBL8088611 | 0.85 | EPHX2 (0.57) | GPR119EPHX2ALKHRH3 | |
| SCHEMBL31071566 | 0.85 | GPR119 (0.58) | GPR119EPHX2HRH3 | |
| SCHEMBL8088637 | 0.84 | GPR119 (0.57) | GPR119EPHX2HRH3 | |
| SCHEMBL15888739 | 0.83 | GPR119 (0.61) | GPR119ALKHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |