Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088595 | 0.86 | GPR119 (0.49) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL18639877 | 0.85 | SCN9A (0.53) | GPR119 | |
| SCHEMBL4689209 | 0.83 | GPR6 (0.40) | GPR119 | |
| SCHEMBL223791 | 0.83 | GPR119 (0.64) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3085652 | 0.83 | GPR119 (0.55) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29964750 | 0.83 | GPR119 (0.59) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30140081 | 0.82 | GPR119 (0.47) | GPR119PDE4BTBK1KDM1A | |
| SCHEMBL31583681 | 0.82 | GPR119 (0.54) | GPR119 | |
| SCHEMBL29825828 | 0.81 | GPR119 (0.47) | GPR119TBK1 | |
| SCHEMBL1142588 | 0.81 | GPR119 (0.53) | GPR119PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |