Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084396 | 1.00 | DRD2 (0.49) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8087998 | 1.00 | DRD2 (0.49) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8076451 | 1.00 | DRD2 (0.49) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8087996 | 1.00 | DRD2 (0.49) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8084398 | 1.00 | DRD2 (0.49) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8076453 | 1.00 | DRD2 (0.49) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8089638 | 1.00 | DRD2 (0.49) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8083758 | 0.98 | DRD2 (0.50) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8083754 | 0.98 | DRD2 (0.50) | DRD2SPHK1L3MBTL1HTR3ALSS | |
| SCHEMBL8922581 | 0.92 | SPHK1 (0.48) | DRD2SPHK1LSSSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| US-5868961-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0632044-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-5641431-A | Silacyclohexanone compound and a method of preparing a silacyclohexane-type liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0673942-A1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0632044-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |