Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 9/20 | 0.53 |
| ▸ | TOP2A | P11388 | 6/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689460 | 0.91 | MEN1 (0.55) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL6773817 | 0.91 | MEN1 (0.57) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL7852654 | 0.90 | MEN1 (0.56) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9162172 | 0.90 | CACNA1F (0.64) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9687713 | 0.87 | GSK3B (0.54) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9689368 | 0.87 | MEN1 (0.53) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9741404 | 0.87 | MEN1 (0.56) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9088549 | 0.84 | MEN1 (0.51) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL9585430 | 0.82 | GSK3B (0.57) | MEN1KMT2APOLBKCNH2CACNA1F | |
| SCHEMBL5704411 | 0.82 | GSK3B (0.66) | MEN1KMT2APOLBKCNH2CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520240-A1 | 7-Isoindolinyl-quinolone and naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-12-30 | — | — | EP | claimed |
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| US-5739339-A | BACTERICIDES, ANTIPROTOZOA AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| US-5464796-A | Bactericides and feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-07 | — | — | US | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0520240-A1 | 7-Isoindolinyl-quinolone and naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |