Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 4/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688639 | 0.90 | GSK3B (0.60) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL8089652 | 0.87 | MEN1 (0.58) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL9689327 | 0.86 | GSK3B (0.54) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL7852654 | 0.85 | MEN1 (0.56) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL12674057 | 0.85 | GSK3B (0.63) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL1345439 | 0.84 | GSK3B (0.55) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL9741615 | 0.84 | GSK3B (0.53) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL9689460 | 0.83 | MEN1 (0.55) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL9688692 | 0.83 | POLB (0.65) | GSK3BMEN1KMT2APOLBCACNA1F | |
| SCHEMBL9162172 | 0.82 | CACNA1F (0.64) | GSK3BMEN1KMT2APOLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5097032-A | Quinoline- and naphthyridine carboxylic acids, salts | WARNER-LAMBERT COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0265230-B1 | SUBSTITUTED-6-FLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACIDS, DERIVATIVES THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS, AND PROCESSES FOR PRODUCING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |
| US-4822801-A | 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0265230-A1 | Substituted-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acids, derivatives thereof, pharmaceutical compositions comprising the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |