Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640978 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BNPC1GLSPOLB | |
| SCHEMBL5435795 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BNPC1GLSPOLB | |
| SCHEMBL28302050 | 0.79 | ACACB (0.52) | MTNR1AMTNR1BNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28303465 | 0.79 | ACACB (0.52) | MTNR1AMTNR1BNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4442263 | 0.79 | ACACB (0.52) | MTNR1AMTNR1BNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL262459 | 0.77 | AKR1C3 (0.50) | LMNAALDH1A1GAAL3MBTL1POLB | |
| SCHEMBL2171847 | 0.77 | AKR1C3 (0.50) | LMNAALDH1A1GAAL3MBTL1POLB | |
| SCHEMBL261617 | 0.77 | AKR1C3 (0.50) | LMNAALDH1A1GAAL3MBTL1POLB | |
| SCHEMBL9212485 | 0.77 | NPC1 (0.41) | MTNR1AMTNR1BNPC1CNR2CNR1 | |
| SCHEMBL2684862 | 0.76 | SLC7A5 (0.43) | MTNR1AMTNR1BNPC1GLSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056773-A2 | ANGIOGENESIS TARGETING MOLECULES | RESOLUTION PHARMACEUTICALS INC. (CA) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999040947-A2 | ANGIOGENESIS TARGETING MOLECULES | RESOLUTION PHARMACEUTICALS INC. (CA) | 1999-08-19 | — | — | WO | disclosed |