Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528965 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL8089749 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL30311991 | 0.71 | MAPT (0.48) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL31483318 | 0.67 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL1196622 | 0.67 | PPM1B (0.38) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL917955 | 0.67 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL30449095 | 0.67 | MEN1 (0.48) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL5958889 | 0.66 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL1332360 | 0.66 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL3625848 | 0.66 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |