Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139244 | 0.86 | TSHR (0.67) | ALDH1A1LMNASMN1; SMN2RECQLTSHR | |
| Hydrochloric Acid SCHEMBL21639989 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL30585932 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2KDM4ETSHR | |
| SCHEMBL10353332 | 0.84 | TSHR (0.67) | ALDH1A1LMNASMN1; SMN2RECQLTSHR | |
| SCHEMBL7260670 | 0.84 | TSHR (0.67) | ALDH1A1LMNASMN1; SMN2RECQLTSHR | |
| SCHEMBL10352436 | 0.84 | TSHR (0.67) | ALDH1A1LMNASMN1; SMN2RECQLTSHR | |
| SCHEMBL10352591 | 0.84 | TSHR (0.67) | ALDH1A1LMNASMN1; SMN2RECQLTSHR | |
| SCHEMBL4827117 | 0.83 | TAAR1 (0.57) | ALDH1A1LMNASMN1; SMN2RECQLCYP2C19 | |
| SCHEMBL4827121 | 0.83 | TAAR1 (0.54) | ALDH1A1LMNASMN1; SMN2RECQLCYP2C19 | |
| SCHEMBL14413602 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4ETSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |