Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083451 | 0.89 | MAPK1 (0.40) | MAPK1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8095245 | 0.88 | MAPK1 (0.43) | MAPK1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8098001 | 0.87 | CXCR4 (0.43) | MAPK1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8095265 | 0.87 | SMYD3 (0.48) | MAPK1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8090161 | 0.86 | SPHK1 (0.33) | F10CCR1 | |
| SCHEMBL8095316 | 0.85 | SMN1; SMN2 (0.43) | POLBLMNASMN1; SMN2F10CCR1 | |
| SCHEMBL8098088 | 0.85 | ITGB3 (0.41) | MAPK1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8090137 | 0.85 | NPC1 (0.45) | MAPK1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8091500 | 0.83 | NPC1 (0.45) | MAPK1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8098110 | 0.82 | F2 (0.42) | F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |