SCHEMBL8090311

SCHEMBL8090311

COc1cccc(C2NC(=O)CS2)c1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.54
DDB1 Q16531 1/20 0.50
CRBN Q96SW2 1/20 0.50
HTR2C P28335 2/20 0.47
GAA P10253 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10677945 0.85 GFER (0.52) GFERL3MBTL1DDB1CRBNGAA
SCHEMBL8098478 0.84 GFER (0.51) GFERL3MBTL1GAAMEN1KMT2A
SCHEMBL8099305 0.82 GFER (0.49) GFERL3MBTL1GAASMN1; SMN2
SCHEMBL10675194 0.81 GFER (0.66) GFERL3MBTL1DDB1CRBNGAA
SCHEMBL8089821 0.80 GFER (0.56) GFERL3MBTL1HTR2CGAAMEN1
SCHEMBL6686421 0.80 GFER (0.47) GFERL3MBTL1GAASMN1; SMN2
SCHEMBL8103732 0.79 GFER (0.46) GFERL3MBTL1GAASMN1; SMN2
SCHEMBL10671668 0.78 L3MBTL1 (0.68) GFERL3MBTL1KDM4EMEN1KMT2A
SCHEMBL8098973 0.78 GFER (0.54) GFERL3MBTL1GAAKDM4ESMN1; SMN2
SCHEMBL10675448 0.78 GFER (1.00) GFERL3MBTL1GAAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed
US-4722932-A ANTI-PEPTIC ULCER AGENTS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-02-02 US disclosed
US-4540702-A 2-Substituted-4-thiazolidones KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-09-10 US disclosed