Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27284341 | 0.79 | SMN1; SMN2 (0.41) | TDP1ALDH1A1GFERKMT2APOLB | |
| SCHEMBL27293942 | 0.79 | GFER (0.41) | TDP1ALDH1A1GFERKMT2APOLB | |
| SCHEMBL8089828 | 0.76 | SMN1; SMN2 (0.54) | ALDH1A1GFERKMT2AGAAMAPT | |
| SCHEMBL19471193 | 0.76 | TDP1 (0.57) | TDP1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL8099174 | 0.76 | GFER (0.52) | ALDH1A1GFERKMT2AKDM4EGAA | |
| SCHEMBL26304201 | 0.75 | TDP1 (0.56) | TDP1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL8096825 | 0.73 | TDP1 (0.48) | TDP1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL8089624 | 0.73 | TDP1 (0.48) | TDP1ALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL8103620 | 0.72 | GFER (0.49) | ALDH1A1GFERGAAMAPTSMN1; SMN2 | |
| SCHEMBL8104985 | 0.72 | GFER (0.49) | GFERGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| CN-1039492-C | Herbicides | ZENECA LTD (GB) | 1998-08-12 | — | — | CN | disclosed |
| CN-1095066-A | Weedicide | ZENECA LTD (GB) | 1994-11-16 | — | — | CN | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |