Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096825 | 0.83 | TDP1 (0.48) | TDP1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8090455 | 0.77 | ALDH1A1 (0.49) | TDP1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL26304201 | 0.74 | TDP1 (0.56) | TDP1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8089861 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL8090331 | 0.73 | TDP1 (0.52) | TDP1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8103622 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL19471193 | 0.69 | TDP1 (0.57) | TDP1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL10840857 | 0.69 | TSHR (0.59) | TDP1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL9389991 | 0.68 | ALDH1A1 (0.40) | ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL31406400 | 0.66 | TDP1 (0.53) | TDP1ALDH1A1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |