Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090368 | 0.76 | GUSB (0.45) | GUSBCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL8098712 | 0.76 | NPSR1 (0.46) | NPSR1GUSBCACNA1FCACNA1DCACNA1S | |
| SCHEMBL8090624 | 0.70 | NPSR1 (0.45) | NPSR1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL8106100 | 0.69 | NPSR1 (0.43) | NPSR1GUSBCACNA1FCACNA1DCACNA1S | |
| SCHEMBL9263779 | 0.67 | GUSB (0.42) | NPSR1GUSBCACNA1FCACNA1DCACNA1S | |
| SCHEMBL8090064 | 0.66 | GUSB (0.43) | NPSR1GUSBCACNA1FCACNA1DCACNA1S | |
| SCHEMBL8090125 | 0.65 | GUSB (0.44) | NPSR1GUSBCACNA1FCACNA1DCACNA1S | |
| SCHEMBL8099407 | 0.65 | GUSB (0.45) | GUSBCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL12154445 | 0.64 | NPSR1 (1.00) | NPSR1CYP1A2CYP2C19LMNAALDH1A1 | |
| SCHEMBL8090428 | 0.63 | MAPT (0.40) | GUSBLMNAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |