Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090625 | 0.76 | NPSR1 (0.45) | GUSBLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8089737 | 0.71 | PBRM1 (0.43) | GUSBPBRM1HTR2CLMNAMAPT | |
| SCHEMBL8090521 | 0.71 | ALDH1A1 (0.63) | GUSBPBRM1HTR2CLMNAMAPT | |
| SCHEMBL8098930 | 0.70 | GFER (0.49) | GUSBPBRM1HTR2CSMN1; SMN2ALDH1A1 | |
| SCHEMBL8788750 | 0.69 | PBRM1 (0.43) | GUSBPBRM1HTR2CLMNAMAPT | |
| SCHEMBL8096948 | 0.69 | PBRM1 (0.46) | GUSBPBRM1HTR2CLMNAMAPT | |
| SCHEMBL9801978 | 0.68 | KDM1A (0.44) | GUSBHTR2CLMNAKDM1ARCOR1 | |
| SCHEMBL19732941 | 0.64 | GUSB (0.77) | GUSBLMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL19732940 | 0.64 | GUSB (0.77) | GUSBLMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL10243490 | 0.64 | CETP (0.46) | GUSBPBRM1HTR2CLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |