Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089213 | 1.00 | CCR5 (1.00) | CCR5MEN1KMT2A | |
| SCHEMBL7817654 | 1.00 | CCR5 (1.00) | CCR5MEN1KMT2A | |
| SCHEMBL8089427 | 0.95 | CCR5 (0.90) | CCR5 | |
| SCHEMBL7824856 | 0.94 | CCR5 (0.88) | CCR5MEN1KMT2A | |
| SCHEMBL7824412 | 0.92 | CCR5 (0.85) | CCR5MEN1KMT2A | |
| SCHEMBL7834595 | 0.89 | CCR5 (1.00) | CCR5MEN1KMT2A | |
| SCHEMBL7816189 | 0.89 | CCR5 (0.80) | CCR5 | |
| SCHEMBL7868394 | 0.88 | CCR5 (0.78) | CCR5MEN1KMT2A | |
| SCHEMBL7825654 | 0.88 | CCR5 (0.78) | CCR5MEN1KMT2A | |
| SCHEMBL8082712 | 0.88 | CCR5 (1.00) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166037-A | Pyrrolidine and piperidine modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2000-12-26 | — | — | US | disclosed |