Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090949 | 1.00 | APAF1 (0.65) | APAF1KMT2AMEN1NPSR1RAB9A | |
| Hydrochloric Acid SCHEMBL15792795 | 0.98 | KMT2A (0.63) | APAF1KMT2AMEN1NPSR1RAB9A | |
| Hydrochloric Acid SCHEMBL15792793 | 0.98 | KMT2A (0.63) | APAF1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL2915346 | 0.89 | APAF1 (0.57) | APAF1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL2915347 | 0.89 | APAF1 (0.57) | APAF1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL2921106 | 0.89 | APAF1 (0.57) | APAF1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL30285806 | 0.88 | APAF1 (0.65) | APAF1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL10879125 | 0.86 | APAF1 (0.62) | APAF1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL14943968 | 0.86 | APAF1 (0.62) | APAF1KMT2AMEN1NPSR1RAB9A | |
| Hydrochloric Acid SCHEMBL10624582 | 0.86 | APAF1 (0.62) | APAF1KMT2AMEN1NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007653-A1 | CHIRAL HYDRIDE COMPLEXES | ZEELAND CHEMICALS, INC. (US) | 1998-02-26 | — | — | WO | claimed |
| US-9012631-B2 | 1,3-oxazolidine-2-one-like compound, preparation method and uses thereof | YABANG PHARMACEUTICAL CO., LTD (CN) | 2015-04-21 | — | — | US | disclosed |
| US-20140171640-A1 | 1,3-OXAZOLIDINE-2-ONE-LIKE COMPOUND, PREPARATION METHOD AND USES THEREOF | YABANG PHARMACEUTICAL CO., LTD (CN) | 2014-06-19 | — | — | US | disclosed |
| WO-2012155042-A2 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | ANDERSON DEVELOPMENT COMPANY (US) | 2012-11-15 | — | — | WO | disclosed |
| US-20120289733-A1 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | ANDERSON DEVELOPMENT COMPANY (US) | 2012-11-15 | — | — | US | disclosed |
| US-6090950-A | Chiral hydride complexes | ZEELAND CHEMICALS, INC. (US) | 2000-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289733-A1 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | BRS3, BRSK1, CA4 | APAF1 2999/4885KMT2A 2803/4885MEN1 58/4885 |
| US-20140171640-A1 | 1,3-OXAZOLIDINE-2-ONE-LIKE COMPOUND, PREPARATION METHOD AND USES THEREOF | OXA1L, CYP2C9, CYP1B1 | APAF1 3626/4885KMT2A 2938/4885MEN1 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.