Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736420 | 0.88 | LMNA (0.56) | LMNARAB9AKDM4EDRD2DRD4 | |
| SCHEMBL8088081 | 0.87 | HRH1 (0.51) | LMNARAB9AKDM4ESMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL17261485 | 0.87 | LMNA (0.55) | LMNARAB9AKDM4EDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL17261571 | 0.87 | LMNA (0.55) | LMNARAB9AKDM4EDRD2DRD4 | |
| SCHEMBL2096394 | 0.84 | LMNA (0.52) | LMNARAB9AKDM4EDRD2DRD4 | |
| SCHEMBL27629615 | 0.84 | LMNA (0.59) | LMNARAB9AKDM4EDRD2DRD4 | |
| SCHEMBL8086775 | 0.84 | KDM4E (0.57) | LMNARAB9AKDM4ESMN1; SMN2ATM | |
| SCHEMBL2092821 | 0.83 | LMNA (0.51) | LMNARAB9AKDM4EDRD2DRD4 | |
| SCHEMBL27482174 | 0.83 | LMNA (0.58) | LMNARAB9AKDM4EDRD2DRD4 | |
| SCHEMBL3372534 | 0.82 | LMNA (0.54) | LMNARAB9AKDM4EDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229082-A | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 1999-09-22 | — | — | CN | claimed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| CN-1151746-A | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1997-06-11 | — | — | CN | claimed |
| US-6100404-A | Erythromycin compounds | HOECHST MARION ROUSSEL (FR) | 2000-08-08 | — | — | US | disclosed |
| CN-1151746-A | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1997-06-11 | — | — | CN | disclosed |
| US-5635485-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1997-06-03 | — | — | US | disclosed |