Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091158 | 0.92 | KCNH2 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9046635 | 0.90 | ALDH1A1 (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9095830 | 0.89 | ALDH1A1 (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8083224 | 0.85 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8091252 | 0.84 | KCNH2 (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10374229 | 0.83 | ALDH1A1 (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8094753 | 0.83 | KDM4E (0.57) | ALDH1A1CYP2C9KDM4EHPGDHSD17B10 | |
| SCHEMBL7955893 | 0.83 | ALDH1A1 (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL13715941 | 0.83 | ALDH1A1 (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8092759 | 0.83 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |