Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081233 | 0.94 | AGTR1 (0.74) | AGTR1AGTR2 | |
| SCHEMBL8081267 | 0.94 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL8088517 | 0.92 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL614372 | 0.91 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL8095012 | 0.90 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL29395394 | 0.87 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL9583456 | 0.87 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL9264451 | 0.87 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL8080801 | 0.87 | AGTR1 (0.76) | AGTR1AGTR2 | |
| SCHEMBL9486998 | 0.87 | AGTR1 (0.67) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037349-A | HAVING ANTAGONISTIC PROPERTIES TOWARDS ANGIOTENSIN II CAN BE USED FOR THE TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GMBH (DE) | 2000-03-14 | — | — | US | disclosed |