Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CPS1 | P31327 | 5/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080941 | 0.82 | POLB (0.36) | PREPFAP | |
| SCHEMBL8093405 | 0.75 | DPP4 (0.43) | DPP4PREPFAPDPP7CNR2 | |
| Trifluoroacetic Acid SCHEMBL3741707 | 0.70 | DPP4 (0.41) | DPP4DPP7DPP8 | |
| SCHEMBL8088188 | 0.70 | CPS1 (0.34) | DPP4HCRTR1CPS1DPP8 | |
| SCHEMBL30333846 | 0.69 | POLB (0.45) | DPP4PREPFAPJAK1DPP7 | |
| SCHEMBL3738668 | 0.66 | PREP (0.37) | PREPFAPJAK1HCRTR1HCRTR2 | |
| SCHEMBL15401836 | 0.64 | KDM4E (0.51) | HCRTR1HCRTR2PDE10A | |
| SCHEMBL8089769 | 0.64 | DPP4 (0.44) | DPP4DPP7DPP8 | |
| SCHEMBL30009295 | 0.63 | JAK1 (0.43) | PREPFAPJAK1CNR2CPS1 | |
| SCHEMBL8086528 | 0.62 | DPP4 (0.60) | DPP4FAPDPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |