Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738668 | 0.79 | PREP (0.37) | PREPFAPGPR119 | |
| SCHEMBL8094578 | 0.72 | ITGAV (0.37) | ITGB3ITGA2BMAPK1SCN9A | |
| SCHEMBL3738694 | 0.69 | PREP (0.38) | PREPFAPGPR119 | |
| SCHEMBL14736900 | 0.68 | CTSK (0.50) | POLBITGB3ITGA2B | |
| SCHEMBL6384976 | 0.66 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL6384973 | 0.66 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL8093405 | 0.65 | DPP4 (0.43) | PREPFAP | |
| SCHEMBL14737633 | 0.65 | CTSK (0.41) | POLBITGB3ITGA2BALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL3741707 | 0.65 | DPP4 (0.41) | — | |
| SCHEMBL30333846 | 0.63 | POLB (0.45) | POLBPREPFAPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |