SCHEMBL8091278

SCHEMBL8091278

C=C(C)c1ccc(C(C)CN=C=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.45
STAT3 P40763 1/20 0.36
ACHE P22303 1/20 0.36
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1705584 0.84 MIF (0.53) MIFSTAT3ACHEFFAR1
SCHEMBL2860264 0.82 GBA1 (0.43) MIF
SCHEMBL9220151 0.81 HDAC8 (0.41)
SCHEMBL6066034 0.76 C3AR1 (0.47) MIFFFAR1
SCHEMBL462795 0.75 TAAR1 (0.47) MIFFFAR1
SCHEMBL29022653 0.75 TAAR1 (0.47) MIFFFAR1
SCHEMBL1005881 0.75 MIF (0.42) MIFSTAT3ACHEFFAR1
SCHEMBL5411169 0.75 MIF (0.35) MIF
SCHEMBL9181988 0.75 CYP3A4 (0.46) MIFACHEFFAR1
SCHEMBL23701495 0.73 TSHR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995000573-A1 REACTIVE POLYMERS HAVING PENDANT FLEXIBLE SIDE CHAINS PREPARED FROM ETHYLENICALLY UNSATURATED ISOCYANATES UNION CARBIDE CHEMICALS & PLASTICS (US) 1995-01-05 WO claimed
WO-1995000560-A1 REACTIVE POLYMERS JOHNSON, Karen, L. (US) 1995-01-05 WO claimed
EP-2655536-A2 PHOTOCURABLE DICING DIE BONDING TAPE Henkel Corporation (US) 2013-10-30 EP disclosed
US-8546485-B2 Photocurable dicing die bonding tape HENKEL CORPORATION (US) 2013-10-01 US disclosed
US-20130178585-A1 PHOTOCURABLE DICING DIE BONDING TAPE HENKEL CORPORATION (US) 2013-07-11 US disclosed
WO-2012087780-A2 PHOTOCURABLE DICING DIE BONDING TAPE HENKEL CORPORATION (US) 2012-06-28 WO disclosed
US-6114444-A Curable polyureas BASF CORPORATION (US) 2000-09-05 US disclosed
EP-0981561-A1 FLUOROCHEMICAL COMPOSITION COMPRISING A URETHANE HAVING A FLUOROCHEMICAL OLIGOMER AND A HYDROPHILIC SEGMENT TO IMPART STAIN RELEASE PROPERTIES TO A SUBSTRATE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-03-01 EP disclosed
WO-1998051724-A1 FLUOROCHEMICAL COMPOSITION COMPRISING A URETHANE HAVING A FLUOROCHEMICAL OLIGOMER AND A HYDROPHILIC SEGMENT TO IMPART STAIN RELEASE PROPERTIES TO A SUBSTRATE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-11-19 WO disclosed
EP-0772642-B1 STRONG CARBOXYLIC ACID FUNCTIONAL POLYURETHANE POLYMERS AND BLENDS THEREOF USED IN MAGNETIC RECORDING MEDIA MINNESOTA MINING & MFG (US) 1998-10-07 EP disclosed
EP-0636670-B1 Curable polyureas BASF CORP (US) 1997-10-01 EP disclosed
EP-0772642-A1 STRONG CARBOXYLIC ACID FUNCTIONAL POLYURETHANE POLYMERS AND BLENDS THEREOF USED IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-05-14 EP disclosed
WO-1996004326-A1 STRONG CARBOXYLIC ACID FUNCTIONAL POLYURETHANE POLYMERS AND BLENDS THEREOF USED IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-15 WO disclosed
EP-0636670-A1 Curable polyureas BASF CORPORATION (US) 1995-02-01 EP disclosed
WO-1995000573-A1 REACTIVE POLYMERS HAVING PENDANT FLEXIBLE SIDE CHAINS PREPARED FROM ETHYLENICALLY UNSATURATED ISOCYANATES UNION CARBIDE CHEMICALS & PLASTICS (US) 1995-01-05 WO disclosed
WO-1995000560-A1 REACTIVE POLYMERS JOHNSON, Karen, L. (US) 1995-01-05 WO disclosed
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 US disclosed