Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083532 | 1.00 | MAPT (0.61) | MAPTABCB1KLK7KLK5CA1 | |
| SCHEMBL25540903 | 0.90 | KLK7 (0.67) | MAPTKLK7KLK5CA1CA2 | |
| SCHEMBL13430768 | 0.90 | SIRT2 (0.64) | MAPTKLK7KLK5CA1CA2 | |
| SCHEMBL30043940 | 0.90 | SIRT2 (0.64) | MAPTKLK7KLK5CA1CA2 | |
| SCHEMBL2329138 | 0.90 | KLK7 (0.67) | MAPTKLK7KLK5CA1CA2 | |
| SCHEMBL2329143 | 0.90 | KLK7 (0.67) | MAPTKLK7KLK5CA1CA2 | |
| SCHEMBL22355258 | 0.90 | MAPT (0.54) | MAPTABCB1KLK7KLK5CA1 | |
| SCHEMBL9706024 | 0.88 | KLK7 (0.60) | MAPTKLK7KLK5CA1CA2 | |
| SCHEMBL15253875 | 0.88 | KLK7 (0.60) | MAPTKLK7KLK5CA1CA2 | |
| SCHEMBL3498752 | 0.87 | MAPT (0.56) | MAPTABCB1KLK7KLK5CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015887-A | PREPARING SYNTHETIC MONOMERS BY DEHYDRATIVE COUPLING OF AMINE AND ALCOHOL STARTING REAGENTS | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-18 | — | — | US | disclosed |