Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.53 |
| ▸ | EEF2K | O00418 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85764 | 0.87 | GABBR2 (0.66) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| SCHEMBL11870637 | 0.86 | GABBR2 (0.53) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| Hydrochloric Acid SCHEMBL31385524 | 0.85 | GABBR2 (0.63) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| Water SCHEMBL1502204 | 0.85 | GABBR2 (0.63) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| Water SCHEMBL1502206 | 0.85 | GABBR2 (0.63) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| SCHEMBL11864278 | 0.83 | GABBR2 (0.50) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| SCHEMBL11867839 | 0.81 | GABBR2 (0.47) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| SCHEMBL10709710 | 0.79 | GABBR2 (0.43) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| SCHEMBL23801955 | 0.78 | GABBR2 (0.55) | GABBR2GABBR1EEF2KSRCCYP1A2 | |
| SCHEMBL23816616 | 0.77 | GABBR2 (0.44) | GABBR2GABBR1EEF2KSRCCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627425-B1 | 3-OXO-1,4-BENZOTHIAZINE DERIVATIVE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5496817-A | TREATMENT OF CATARACTS; SUPPRESSION OF LIPID PEROXIDE FORMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0627425-A1 | 3-OXO-1,4-BENZOTHIAZINE DERIVATIVE | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |