Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491194 | 0.87 | THRB (0.48) | THRBTSHRPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL27901132 | 0.86 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL5139727 | 0.79 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL10312244 | 0.78 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2462214 | 0.78 | TSHR (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL5505311 | 0.78 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL5725130 | 0.76 | TSHR (0.66) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL27776277 | 0.76 | TSHR (0.56) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8823545 | 0.76 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11964784 | 0.76 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055713-A2 | Water insoluble non-ionic graft copolymer binders | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |