Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.62 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107162 | 0.89 | PTGS1 (0.61) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| SCHEMBL8101589 | 0.89 | PTGS2 (0.61) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL8481799 | 0.88 | PTGS2 (0.60) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| SCHEMBL8480176 | 0.88 | PTGS1 (0.60) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| SCHEMBL8092102 | 0.88 | PTGS1 (0.60) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| SCHEMBL8091401 | 0.87 | PTGS1 (0.60) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| SCHEMBL8481953 | 0.86 | PTGS1 (0.59) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| SCHEMBL8099550 | 0.86 | PTGS1 (0.59) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| SCHEMBL8100691 | 0.85 | PTGS1 (0.58) | PTGS2PTGS1CCR2ALDH1A1TP53 | |
| Methylamine SCHEMBL8479365 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1CCR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |