Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248479 | 1.00 | CTSK (1.00) | CTSKCTSB | |
| SCHEMBL2243768 | 0.92 | CTSK (0.84) | CTSKCTSB | |
| SCHEMBL2243771 | 0.91 | CTSK (1.00) | CTSKCTSB | |
| SCHEMBL2244077 | 0.91 | CTSK (1.00) | CTSKCTSB | |
| SCHEMBL2246081 | 0.91 | CTSK (1.00) | CTSKCTSB | |
| SCHEMBL2239705 | 0.91 | CTSK (0.83) | CTSKCTSB | |
| SCHEMBL2243509 | 0.89 | CTSK (1.00) | CTSKCTSB | |
| SCHEMBL2248488 | 0.89 | CTSK (0.82) | CTSKCTSB | |
| SCHEMBL2245036 | 0.89 | CTSK (1.00) | CTSKCTSB | |
| SCHEMBL2241257 | 0.88 | CTSK (1.00) | CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001129-A9 | 1-CYANOCYCLOPROPYL-DERIVATIVES AS CATHEPSIN K INHIBITORS | ASTRAZENECA AB (SE) | 2010-02-04 | — | — | WO | disclosed |
| WO-2009001129-A1 | 1-CYANOCYCLOPROPYL-DERIVATIVES AS CATHEPSIN K INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |