Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949513 | 0.73 | ATM (0.47) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL5480792 | 0.71 | LMNA (0.31) | — | |
| SCHEMBL28780914 | 0.70 | TSHR (0.50) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL4740024 | 0.69 | ATM (0.34) | ATMHCAR2TSHRHPGD | |
| SCHEMBL9577732 | 0.69 | ATM (0.74) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL7720268 | 0.69 | ATM (0.74) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL6864034 | 0.69 | TSHR (0.38) | ATMHCAR2TSHRHPGDCES2 | |
| SCHEMBL9577725 | 0.69 | ATM (0.74) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL11749631 | 0.68 | HCAR2 (0.38) | ATMHCAR2 | |
| SCHEMBL11747402 | 0.68 | HCAR2 (0.38) | ATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006130-A1 | Fumaric acid diester resin composition, cross-linked fumaric acid diester resin and process | NOF CORPORATION (JP) | 2000-06-07 | — | — | EP | disclosed |