Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099839 | 0.91 | TACR1 (0.54) | TACR1TACR2 | |
| SCHEMBL8582371 | 0.91 | TACR1 (0.54) | TACR1TACR2 | |
| SCHEMBL4258143 | 0.86 | TACR1 (0.56) | TACR1TACR2 | |
| SCHEMBL6594434 | 0.85 | TACR1 (0.55) | TACR1TACR2 | |
| SCHEMBL9110425 | 0.84 | TACR2 (0.61) | TACR1TACR2 | |
| SCHEMBL6598186 | 0.82 | TACR1 (0.51) | TACR1TACR2 | |
| SCHEMBL6424008 | 0.80 | TACR2 (0.44) | TACR1TACR2 | |
| SCHEMBL6424010 | 0.80 | TACR2 (0.44) | TACR1TACR2 | |
| SCHEMBL493651 | 0.80 | TACR1 (0.48) | TACR1 | |
| SCHEMBL3766497 | 0.80 | TACR1 (0.48) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013644-A | AIDS THERAPY | MERCK & CO., INC. (US) | 2000-01-11 | — | — | US | disclosed |
| US-5869496-A | TREATING ASTHMA, EMESIS | MERCK & CO., INC. (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0681571-B1 | SPIRO-SUBSTITUTED AZACYCLES AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1998025604-A1 | SPIRO-SUBSTITUTED AZACYCLES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0681571-A1 | SPIRO-SUBSTITUTED AZACYCLES AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994017045-A1 | SPIRO-SUBSTITUTED AZACYCLES AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-08-04 | — | — | WO | disclosed |