Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424008 | 1.00 | TACR2 (0.44) | TACR2TACR1 | |
| SCHEMBL6425190 | 0.91 | TACR2 (0.45) | TACR2TACR1 | |
| SCHEMBL6425195 | 0.91 | TACR2 (0.45) | TACR2TACR1 | |
| SCHEMBL6595201 | 0.85 | TACR2 (0.50) | TACR2TACR1 | |
| SCHEMBL9110425 | 0.83 | TACR2 (0.61) | TACR2TACR1 | |
| SCHEMBL6595186 | 0.82 | TACR2 (0.47) | TACR2TACR1 | |
| SCHEMBL8092249 | 0.80 | TACR1 (0.53) | TACR2TACR1 | |
| SCHEMBL6592845 | 0.78 | TACR2 (0.44) | TACR2TACR1 | |
| SCHEMBL8308170 | 0.76 | TACR2 (0.42) | TACR2TACR1 | |
| SCHEMBL6422198 | 0.76 | NOTUM (0.40) | TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077942-B1 | CARBOXY SUBSTITUTED CARBOXAMIDE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | AVENTIS PHARMA INC (US) | 2005-01-12 | — | — | EP | disclosed |
| US-6316445-B1 | TACHYKININ RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. | 2001-11-13 | — | — | US | disclosed |
| EP-1077942-A1 | CARBOXY SUBSTITUTED CARBOXAMIDE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059972-A1 | CARBOXY SUBSTITUTED CARBOXAMIDE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-11-25 | — | — | WO | disclosed |