SCHEMBL8092250

SCHEMBL8092250

CCc1cc(C)c(Nc2ccc(Nc3c(C)cc(CC)cc3C)c3c2C(=O)c2ccccc2C3=O)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.50
▸ TDP1 Q9NUW8 5/20 0.50
▸ MAPK1 P28482 4/20 0.50
▸ L3MBTL1 Q9Y468 4/20 0.50
▸ MEN1 O00255 4/20 0.50
▸ KMT2A Q03164 4/20 0.50
▸ ALDH1A1 P00352 3/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ NPSR1 Q6W5P4 3/20 0.50
▸ NSD2 O96028 3/20 0.50
▸ POLB P06746 3/20 0.50
▸ THRB P10828 2/20 0.50
▸ HPGD P15428 2/20 0.50
▸ RECQL P46063 2/20 0.50
▸ P2RY1 P47900 2/20 0.50
▸ RAB9A P51151 4/20 0.46
▸ NPC1 O15118 3/20 0.46
▸ LMNA P02545 2/20 0.46
▸ P2RY4 P51582 6/20 0.44
▸ MTOR P42345 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20520540 0.93 MAPT (0.47) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL9176387 0.88 P2RY4 (0.47) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL11596468 0.87 MAPT (0.53) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL1047268 0.86 MAPT (0.64) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL29369318 0.86 MAPT (0.64) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL11054566 0.84 MAPT (0.56) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL6254882 0.83 MEN1 (0.51) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL18294468 0.83 MAPT (0.51) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL16985231 0.83 MAPT (0.51) MAPTTDP1MAPK1L3MBTL1MEN1
SCHEMBL18294471 0.83 ALDH1A1 (0.57) MAPTTDP1MAPK1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6051360-A A REACTION PRODUCT OF A CHROMOPHORIC NUCLEUS AND A BISPHENOL; EXCELLENT SOLUBILITY IN SOLVENTS AND BINDER RESINS; COLOR FILTERS FOR DISPLAY DEVICES SUCH AS LIQUID CRYSTAL TELEVISION AND COLOR SEPARATION FILTERS FOR IMAGE PICKUP TUBES MITSUI CHEMICALS, INC. (JP) 2000-04-18 — — US disclosed
EP-0633296-B1 Novel dyestuffs and their use MITSUI CHEMICALS INC (JP) 1999-10-13 — — EP disclosed
US-5773172-A SOLVENT AND BINDER SOLUBILITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-30 — — US disclosed
EP-0564237-B1 Preparation of color filter and photo-setting resin therefor MITSUI TOATSU CHEMICALS (JP) 1998-03-11 — — EP disclosed
US-5482804-A Resin composition for color filter MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-01-09 — — US disclosed
EP-0633296-A1 Novel dyestuffs and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-01-11 — — EP disclosed
EP-0564237-A2 Preparation of color filter and photo-setting resin therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-10-06 — — EP disclosed
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