Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.69 |
| ▸ | CA4 | P22748 | 1/20 | 0.69 |
| ▸ | CA6 | P23280 | 1/20 | 0.69 |
| ▸ | CA7 | P43166 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449014 | 0.88 | AKR1B1 (1.00) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL72309 | 0.88 | AKR1B1 (1.00) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4284420 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| Phosphine SCHEMBL28850721 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28407811 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28714918 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8622012 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL10886656 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| Potassium SCHEMBL4278025 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28331403 | 0.86 | AKR1B1 (0.95) | AKR1B1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051549-A1 | TREATMENT OF FABRICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2000-11-15 | — | — | EP | claimed |
| WO-1999039039-A1 | TREATMENT OF FABRICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1999-08-05 | — | — | WO | claimed |