SCHEMBL30449014

SCHEMBL30449014

O=C(O)Cc1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 1.00
TDP1 Q9NUW8 2/20 0.57
HSPA5 P11021 1/20 0.56
TTR P02766 1/20 0.53
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
POLB P06746 1/20 0.52
GAA P10253 1/20 0.52
THRB P10828 1/20 0.52
DNMT1 P26358 1/20 0.52
RECQL P46063 1/20 0.52
CASP6 P55212 1/20 0.52
KMT2A Q03164 1/20 0.52
MCL1 Q07820 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CYP2D6 P10635 1/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72309 1.00 AKR1B1 (1.00) AKR1B1TDP1HSPA5TTRKDM4E
SCHEMBL28714918 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
Potassium SCHEMBL4278025 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
SCHEMBL27558027 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
SCHEMBL4284420 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
Ammonia Solution, Strong SCHEMBL10886656 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
Phosphine SCHEMBL28850721 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
Hydrochloric Acid SCHEMBL8622012 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
SCHEMBL28407811 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E
SCHEMBL28331403 0.98 AKR1B1 (0.95) AKR1B1TDP1HSPA5TTRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MARVELBIOME INC (US) 2026-04-02 US disclosed
EP-4587116-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2025-07-23 EP disclosed
WO-2024058984-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2024-03-21 WO disclosed
US-20240066075-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING EYE DISORDERS MarvelBiome, Inc. 2024-02-29 US disclosed
CN-116751348-A Triblock copolymer, preparation method and application 郑州大学 2023-09-15 CN disclosed
US-20230190709-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2023-06-22 US disclosed
EP-3432713-B1 NON-ALPHA SUBSTITUTED PEROXY ACIDS AND USES THEREOF STEPAN CO (US) 2023-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES IAPP, GPR119, FAHD1 AKR1B1 142/4885TDP1 3482/4885HSPA5 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.