Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CBS | P35520 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094041 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8095159 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8094146 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8093301 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8099844 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8098721 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8101181 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8100036 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8086884 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R | |
| SCHEMBL8094826 | 1.00 | PTGS2 (0.44) | PTGS2MAPTSMN1; SMN2CYP3A4IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |