SCHEMBL8092480

SCHEMBL8092480

CCC(C)(OC(=O)/C=C/C(=O)OC(C)(CC)C(C)C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 7/20 0.36
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
THRB P10828 1/20 0.31
CTSK P43235 1/20 0.30
TSHR P16473 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092491 0.92 HCAR2 (0.48) ATMHCAR2TSHRMAPT
SCHEMBL8092483 0.92 HCAR2 (0.48) ATMHCAR2TSHRMAPT
SCHEMBL16139527 0.83 TSHR (0.44) THRBTSHR
SCHEMBL11747402 0.79 HCAR2 (0.38) ATMHCAR2KEAP1NFE2L2
SCHEMBL14990863 0.79 TSHR (0.33) TSHR
SCHEMBL11749631 0.79 HCAR2 (0.38) ATMHCAR2KEAP1NFE2L2
SCHEMBL15355481 0.79 ALDH1A1 (0.34) ATMTHRBMAPTNPSR1
SCHEMBL15355479 0.79 ALDH1A1 (0.34) ATMTHRBMAPTNPSR1
SCHEMBL8102281 0.77 HCAR2 (0.50) ATMHCAR2TSHR
SCHEMBL21847337 0.77 GAA (0.43) TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8575288-B2 Photocurable resin composition for forming overcoats RGB pixels black matrixes or spacers in color filter production, and color filters DAI NIPPON PRINTING CO., LTD. (JP) 2013-11-05 US disclosed
EP-1006130-A1 Fumaric acid diester resin composition, cross-linked fumaric acid diester resin and process NOF CORPORATION (JP) 2000-06-07 EP disclosed